Friday, May 4, 2012

Basal ganglia calcification on CT

The faint white stippling in the basal ganglia region is calcification.
Calcification is better seen on a CT scan than MRI. MRI will show low intensity on T2 which is often missed. Causes include
1. Metabolic: hypocalcemia due to hypoparathyroidism, pseudohypoparathyroidism and hyperparathyroidism
2. Birth asphyxia
3. Infections: TORCH, CNS TB, CNS HIV, neurocysticercosis, toxoplasmosis
4. Genetic disorders- mitochondrial, Hallervorden Spatz disease
5. Toxins- CO and lead poisoning.
6. Idiopathic- Fahr disease

A good site to read more is :
http://www.ncbi.nlm.nih.gov/books/NBK1421/

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